Mobile and Flexible
All-In-One Joint Health Formula TM
All-In-One Joint Health Formula TM
FORMULA INGREDIENTS
Here’s The Individual Description of The Eleven (11) Select ‘Chondroprotective Nutrients’ Contained in Our Proprietary Mobile and Flexible All-In-One Joint Health Formula TM Nutritional Supplement
*Non-Denatured WHEY PROTEIN ISOLATE
Athletes effectively use Whey Protein Isolate (WPI) in their training program to enhance performance and increase lean muscle mass. Furthermore, due to its abundant supply of the three BCAAs muscle-building amino acids (namely Leucine, Isoleucine and Valine), WPI substantially enhances muscle growth and recovery, resulting in added muscle strength, which aids in supporting the entire musculoskeletal system, including nourishing and invigorating Articular (Joint) Cartilage, thus either preventing or helping to repair osteoarthritic degeneration.
- Augusto Agostini-Chapel, Ph. D.
What is Whey Protein
It is one of the two proteins found in milk (the other is Casein).
Its history resembles that of the “ugly duckling” becoming “the beautiful swan”, as Whey Protein has gone from being (just two decades ago) the waste product of cheese-making to being one of today’s most sought-after functional food (Zoonutrient) products in the market, as per its remarkable and plentiful nutritional and overall health-benefiting value to humanity.
It first became a popular nutritional supplement as the best source
of good protein among bodybuilders and athletes in general, but now its well-gained reputation, as arguably the healthiest and most complete of all foods available in today’s market, has gained it widespread use-support among people of all ages.
Whey proteins refer to the group of protein fractions that separate out from the Casein during cheese-making. Depending on the purpose for its utilization, these protein fractions are purified at different levels of concentration that go from its lowest as simply Whey Powder (11% to 15% protein), to the most commonly used Whey Concentrate (25% to 89% protein), and reaching its very finest stage of purification and quality as Whey Protein Isolate (“the beautiful swan”, remember !!) at over 90% pure protein – like the one exclusively utilized in the processing of our Mobile and Flexible All-In-One Joint Health Formula TM proprietary formulation.
Its history resembles that of the “ugly duckling” becoming “the beautiful swan”, as Whey Protein has gone from being (just two decades ago) the waste product of cheese-making to being one of today’s most sought-after functional food (Zoonutrient) products in the market, as per its remarkable and plentiful nutritional and overall health-benefiting value to humanity.
It first became a popular nutritional supplement as the best source
of good protein among bodybuilders and athletes in general, but now its well-gained reputation, as arguably the healthiest and most complete of all foods available in today’s market, has gained it widespread use-support among people of all ages.
Whey proteins refer to the group of protein fractions that separate out from the Casein during cheese-making. Depending on the purpose for its utilization, these protein fractions are purified at different levels of concentration that go from its lowest as simply Whey Powder (11% to 15% protein), to the most commonly used Whey Concentrate (25% to 89% protein), and reaching its very finest stage of purification and quality as Whey Protein Isolate (“the beautiful swan”, remember !!) at over 90% pure protein – like the one exclusively utilized in the processing of our Mobile and Flexible All-In-One Joint Health Formula TM proprietary formulation.
Let’s Get Acquainted with Whey Protein Isolate and the Special Nutrient-Retaining Process of Our Formulation (called MANPPRO TM )
Whey Protein Isolate is state-of-the-art , crème-de-la-crème
protein, it’s Nature’s nutritional powerhouse, let’s learn why.
There’s a huge difference in quality between proteins, they’re definitely not equal. In terms of biological value, Whey Protein Isolate is an outstandingly superior protein. By weight and quality, WPI is over 90% pure protein, much purer than the commonly used concentrate. It is highly digestible, allowing it to be absorbed and assimilated much faster by our body. Despite its high purification, and thanks to our proprietary, non-denatured, low temperature, nutrient-retaining technique called MANPPRO TM (Microfiltration All-Nutrients Preservation Process), we’re able to safeguard almost to perfection (close to 99% non-denatured) its wide spectrum of highly-beneficial protein fractions’ bioactive properties.
Through this special production process, we are able to separate
and remove - almost completely - those specific components considered undesirable for consumers’ health such as lactose, fat, ash, and cholesterol. However, we simultaneously exert extreme care in handling the whey with low temperature filtering via our proprietary technique so that the important bioactive elements (protein sub-fractions) found in the product are not damaged and are allowed to remain in an almost perfect (99%) non-denatured intact – state. These components (listed below) will support muscle mass enhancement, boost energy via a more efficient metabolism, and - last but not least – help us attain a more efficient overall Immune System function.
protein, it’s Nature’s nutritional powerhouse, let’s learn why.
There’s a huge difference in quality between proteins, they’re definitely not equal. In terms of biological value, Whey Protein Isolate is an outstandingly superior protein. By weight and quality, WPI is over 90% pure protein, much purer than the commonly used concentrate. It is highly digestible, allowing it to be absorbed and assimilated much faster by our body. Despite its high purification, and thanks to our proprietary, non-denatured, low temperature, nutrient-retaining technique called MANPPRO TM (Microfiltration All-Nutrients Preservation Process), we’re able to safeguard almost to perfection (close to 99% non-denatured) its wide spectrum of highly-beneficial protein fractions’ bioactive properties.
Through this special production process, we are able to separate
and remove - almost completely - those specific components considered undesirable for consumers’ health such as lactose, fat, ash, and cholesterol. However, we simultaneously exert extreme care in handling the whey with low temperature filtering via our proprietary technique so that the important bioactive elements (protein sub-fractions) found in the product are not damaged and are allowed to remain in an almost perfect (99%) non-denatured intact – state. These components (listed below) will support muscle mass enhancement, boost energy via a more efficient metabolism, and - last but not least – help us attain a more efficient overall Immune System function.
Whey Protein Isolate’s Is The Absolute Leader in Biological Value (BV) Among All Protein Sources
It’s very important to understand the nutritional superiority of Whey Protein Isolate (WPI) among all protein sources for our consumption, and the scientific data confirms this fact.
In terms of Biological Value (BV), which refers to how well and how quickly the human body utilizes the protein that it consumes, Whey Protein Isolate leads the way - galloping - with the highest Biological Value (BV) rating at 154, while been distantly followed by Whey Protein Concentrate with 104 BV, Eggs with 100 BV, Milk with 91 BV, and Beef with 80 BV.
In terms of Biological Value (BV), which refers to how well and how quickly the human body utilizes the protein that it consumes, Whey Protein Isolate leads the way - galloping - with the highest Biological Value (BV) rating at 154, while been distantly followed by Whey Protein Concentrate with 104 BV, Eggs with 100 BV, Milk with 91 BV, and Beef with 80 BV.
Whey Protein Isolate : The Best Source of Branched Chain Amino Acids (BCAAs), Which Are Essential For Muscle Growth and Repair
Maintaining adequate amounts of Protein in muscles and organs is essential to Life, and Muscles play a vital role in supporting overall health and wellness, not only during our younger years but also as we advance in age.
Growing, keeping and repairing our muscles is critically important for our good overall metabolic health (including the much needed sensitivity to both Insulin and Leptin), as well as for our weight management, our bone strength and for enhancing our resilience to stress and disease.
Accordingly, for this essential purpose of producing enough Protein for our needs, the human body utilizes its building blocks - called Amino Acids, of which there are 21 common amino acids officially recognized by science, consisting of 12 nonessential and 9 essential amino acids.
Among these 9 essential proteinogenic amino acids, there are three (3) called Branched Chain Amino Acids (BCAAs) – named like this as per their molecular structure – that importantly make up to 75% of our body’s total muscle tissue. The names of these key muscle-building and muscle-repairing BCCAs are Leucine, Isoleucine and Valine.
And it’s extremely important to say that Whey Protein Isolate is the very best source of Protein and of BCAAs available to humans at all ages.
Growing, keeping and repairing our muscles is critically important for our good overall metabolic health (including the much needed sensitivity to both Insulin and Leptin), as well as for our weight management, our bone strength and for enhancing our resilience to stress and disease.
Accordingly, for this essential purpose of producing enough Protein for our needs, the human body utilizes its building blocks - called Amino Acids, of which there are 21 common amino acids officially recognized by science, consisting of 12 nonessential and 9 essential amino acids.
Among these 9 essential proteinogenic amino acids, there are three (3) called Branched Chain Amino Acids (BCAAs) – named like this as per their molecular structure – that importantly make up to 75% of our body’s total muscle tissue. The names of these key muscle-building and muscle-repairing BCCAs are Leucine, Isoleucine and Valine.
And it’s extremely important to say that Whey Protein Isolate is the very best source of Protein and of BCAAs available to humans at all ages.
Whey Protein Isolate’s Other Valuable Health - Benefiting Components
Our formulation preserves - via its unique processing technique* - all of the bioactive whey protein sub-fractions, such as Beta-lactoglobulin, Alpha-lactalbumin, Immunoglobulins (mostly IgG, with IgA and IgM),
Bovine Serum Albumin, Glycomacropeptide, Lactoferrin, Lactoperoxidase, and Lyzozyme.
Regarding Beta-lactoglobulin, we must point out that this is the most abundant component in whey protein (50% to 75%), being rich in the trio of amino acids which specialize in enhancing muscle mass and energy boosting called BCAAs (Branched-Chain Amino Acids), namely Leucine, Isoleucine and Valine. As to Alpha-lactalbumin,it’s important to know that this is the second most abundant whey protein component (12% to 24%), being high in essential amino acid Tryptophan, which has been found to help sleep better and improve mood under stress as well as helping control cravings, thus an aid for appetite control, so important for weight management.This component is also capable of binding mineral Calcium, and is the most abundant protein in the composition of human breast milk.
Up to 15% of whey protein is composed of important Immune System-protective Immunoglobulins and of Bovine Serum Albumin, rich in Glutathione’s most potent precursor - Cysteine.
Meanwhile, glycoprotein Lactoferrin is also a Cysteine-rich sub-fraction, thus it’s not only a good promoter of powerful antioxidant Glutathione but also possesses important anti-inflammatory, anti-viral and immuno-modulating properties of its own. And to round up this brief look at this large number of health-giving protein fractions found in whey, there’s also one called Glycomacropeptide, which besides helping to inhibit the formation of dental cavities , is also another nutritional asset for controlling appetite.
It is a complete protein as it contains all the amino acids utilized via digestion and nutrient assimilation by our organism for the building and regeneration of every single cell in our body (muscles, blood, bones, cartilage, skin, hair, etc.). Additionally, it offers the consumer one of the highest concentrations of the remarkable muscle tissue-builders and energy-boosting Branched Chain Amino Acids trio (BCAAs : Leucine, Isoleucine and Valine), that’s close to 25% of its total amino acid contents.
Furthermore, via our proprietary bioactive protein fractions - preserving processing technique (previously described) – our formulation may provide a wide range of health-enhancing properties, such as : Antioxidant (that neutralize harmful Free Radicals), Anti- Viral / Anti-Bacterial, Hypolipidemic (lowering bad cholesterol and triglycerides), Anti-Hypertensive (lowering High Blood Pressure), plus becoming our Liver’s best detoxifying agent, as well as it strongly improves our foremost-important Immune System function.
Bovine Serum Albumin, Glycomacropeptide, Lactoferrin, Lactoperoxidase, and Lyzozyme.
Regarding Beta-lactoglobulin, we must point out that this is the most abundant component in whey protein (50% to 75%), being rich in the trio of amino acids which specialize in enhancing muscle mass and energy boosting called BCAAs (Branched-Chain Amino Acids), namely Leucine, Isoleucine and Valine. As to Alpha-lactalbumin,it’s important to know that this is the second most abundant whey protein component (12% to 24%), being high in essential amino acid Tryptophan, which has been found to help sleep better and improve mood under stress as well as helping control cravings, thus an aid for appetite control, so important for weight management.This component is also capable of binding mineral Calcium, and is the most abundant protein in the composition of human breast milk.
Up to 15% of whey protein is composed of important Immune System-protective Immunoglobulins and of Bovine Serum Albumin, rich in Glutathione’s most potent precursor - Cysteine.
Meanwhile, glycoprotein Lactoferrin is also a Cysteine-rich sub-fraction, thus it’s not only a good promoter of powerful antioxidant Glutathione but also possesses important anti-inflammatory, anti-viral and immuno-modulating properties of its own. And to round up this brief look at this large number of health-giving protein fractions found in whey, there’s also one called Glycomacropeptide, which besides helping to inhibit the formation of dental cavities , is also another nutritional asset for controlling appetite.
It is a complete protein as it contains all the amino acids utilized via digestion and nutrient assimilation by our organism for the building and regeneration of every single cell in our body (muscles, blood, bones, cartilage, skin, hair, etc.). Additionally, it offers the consumer one of the highest concentrations of the remarkable muscle tissue-builders and energy-boosting Branched Chain Amino Acids trio (BCAAs : Leucine, Isoleucine and Valine), that’s close to 25% of its total amino acid contents.
Furthermore, via our proprietary bioactive protein fractions - preserving processing technique (previously described) – our formulation may provide a wide range of health-enhancing properties, such as : Antioxidant (that neutralize harmful Free Radicals), Anti- Viral / Anti-Bacterial, Hypolipidemic (lowering bad cholesterol and triglycerides), Anti-Hypertensive (lowering High Blood Pressure), plus becoming our Liver’s best detoxifying agent, as well as it strongly improves our foremost-important Immune System function.
Whey Protein Isolate Is The Quintessential Enhancer of Glutathione, Our Body’s Master “LifeProtecting and Extending” Antioxidant
As we’ll learn about it in full detail by reading the section of this handbook, entitled “The Master Antioxidant GLUTATHIONE, Our Body’s Best Defense Against Oxidative Stress, Arguably The Culprit of Chronic Disease and Premature Aging” – this extraordinarily beneficial Antioxidant which resides in nearly all our body living cells, and according to lead scientists, vital for human life, is obtained by us in an efficient (bioavailable), abundant way by daily consuming Whey Protein Isolate.
Glutathione (GSH) is one of the only three naturally-occurring, endogeneous Antioxidants in our body (the others are Catalase and SOD or Superoxide Dismutase), and is known as a tri-peptide , that is, a small protein molecule composed of 3 amino acids, namely : Cysteine, Glutamate, and Glycine called GSH precursors (building blocks).
Each serving of non-denatured Whey Protein Isolate provides an abundant provision of all these three amino acids that comprise Glutathione (GSH), thus making it a premier functional food source of this utmost important Antioxidant.
Glutathione (GSH) is one of the only three naturally-occurring, endogeneous Antioxidants in our body (the others are Catalase and SOD or Superoxide Dismutase), and is known as a tri-peptide , that is, a small protein molecule composed of 3 amino acids, namely : Cysteine, Glutamate, and Glycine called GSH precursors (building blocks).
Each serving of non-denatured Whey Protein Isolate provides an abundant provision of all these three amino acids that comprise Glutathione (GSH), thus making it a premier functional food source of this utmost important Antioxidant.
*FORTIGEL® Hydrolyzed Bioactive Bovine Collagen Peptides
Promoting Joint Regeneration and Rejuvenation
Our nutritional supplement Mobile and Flexible All-In-One Joint Health Formula TM – provides 10,000 mg (10 grams) per sachet serving of FORTIGEL® Collagen Peptides as key component of our natural, drug-free comprehensive solution to joint health problems.
This unique, bioactive Collagen Peptides ingredient – backed by numerous human trial research studies – has been proven to act directly on cartilage cells by stimulating the biosynthesis of Collagen and Proteoglycans, which represent 95% of Articular (Joint) Cartilage, and thus showing significant improvement in pain relief, as well as in enhancing joint mobility and flexibility.
This unique, bioactive Collagen Peptides ingredient – backed by numerous human trial research studies – has been proven to act directly on cartilage cells by stimulating the biosynthesis of Collagen and Proteoglycans, which represent 95% of Articular (Joint) Cartilage, and thus showing significant improvement in pain relief, as well as in enhancing joint mobility and flexibility.
Collagen : The Body’s Protein
About 30% of our total body protein is Collagen. Collagen is crucial for mobile joints, stable bones, healthy muscles, strong ligaments and tendons, smooth skin, glossy hair and healthy finger nails. It is one of the primary structural proteins of connective tissues and also abundant in blood vessels, intervertebral discs, the blood-brain barrier, the cornea, dentin and the intestinal wall. Thus, it’s easy to understand that Collagen is indeed a vital component of our whole body.
What are FORTIGEL® Collagen Peptides, and how do they help keep people physically active and mobile
Today, every fourth person suffers from joint problems and the number is continually increasing. The principal cause is
wear and tear of the joint cartilage brought about by age, excess activity and stressed joints. But there is help available
for those in need of joint support. Developed by GELITA, FORTIGEL® Bioactive Collagen Peptides is an innovative ingredient for the regeneration of joint cartilage.
FORTIGEL® Bioactive Collagen Peptides (BCP) are a composition of different specific ‘peptides’ (protein sub-fractions) optimized for specific physiological benefits. The peptides are derived from a highly controlled production process of Collagen which is determined by hydrolyzation conditions. They are optimized to maximize stimulation of the human cell types involved in collagen biosynthesis.
Collagenous protein makes up nearly 70% of cartilage mass. Optimized specific collagen peptides of FORTIGEL® have been proven to activate the growth of new cartilage by stimulating cells helping to ease joint discomfort and make the joints smooth and mobile. By keeping people physically active and mobile, FORTIGEL® can improve quality of life.
wear and tear of the joint cartilage brought about by age, excess activity and stressed joints. But there is help available
for those in need of joint support. Developed by GELITA, FORTIGEL® Bioactive Collagen Peptides is an innovative ingredient for the regeneration of joint cartilage.
FORTIGEL® Bioactive Collagen Peptides (BCP) are a composition of different specific ‘peptides’ (protein sub-fractions) optimized for specific physiological benefits. The peptides are derived from a highly controlled production process of Collagen which is determined by hydrolyzation conditions. They are optimized to maximize stimulation of the human cell types involved in collagen biosynthesis.
Collagenous protein makes up nearly 70% of cartilage mass. Optimized specific collagen peptides of FORTIGEL® have been proven to activate the growth of new cartilage by stimulating cells helping to ease joint discomfort and make the joints smooth and mobile. By keeping people physically active and mobile, FORTIGEL® can improve quality of life.
FORTIGEL® promotes growth of cartilage tissue
The effectiveness of FORTIGEL® has been scientifically proven in numerous studies. According to published research, orally administered FORTIGEL® is absorbed intestinally and accumulates in cartilage.
The ingestion of FORTIGEL® stimulates a statistically significant increase of cartilage tissue metabolism.
The effect of FORTIGEL® Bioactive Collagen Peptides on increased extracellular matrix synthesis is based on two mechanisms:
1) Supply of typical collagen amino acids as valuable
building blocks, and
2) Stimulate cell synthesis.
The ingestion of FORTIGEL® stimulates a statistically significant increase of cartilage tissue metabolism.
The effect of FORTIGEL® Bioactive Collagen Peptides on increased extracellular matrix synthesis is based on two mechanisms:
1) Supply of typical collagen amino acids as valuable
building blocks, and
2) Stimulate cell synthesis.
Accordingly, FORTIGEL®
is an effective Chondroprotective substance for promoting
sustainable joint mobility and flexibility, as :
) It has been scientifically studied to regenerate joint cartilage tissue ;
b) It stimulates the body’s own mechanisms for maintaining healthy joints and optimum mobility, and
c) It promotes joint health naturally with no side effects.
Based on the presented data and on the numerous validated human trial research studies performed over the years that corroborate it, we may conclude that the daily oral administration of FORTIGEL® has a beneficial effect on cartilage tissue. Consequently, supplementation of FORTIGEL® peptides may contribute to the maintenance of joint health and help to preserve mobility and to enhance quality of life of Osteoarthritis (OA) sufferers.
b) It stimulates the body’s own mechanisms for maintaining healthy joints and optimum mobility, and
c) It promotes joint health naturally with no side effects.
Based on the presented data and on the numerous validated human trial research studies performed over the years that corroborate it, we may conclude that the daily oral administration of FORTIGEL® has a beneficial effect on cartilage tissue. Consequently, supplementation of FORTIGEL® peptides may contribute to the maintenance of joint health and help to preserve mobility and to enhance quality of life of Osteoarthritis (OA) sufferers.
*BiovaFlex®
EGG MEMBRANE
(Hydrolyzed, Water-Soluble, Elastin-rich)
Its Components :
Collagen – A fibrous protein that supports cartilage and connective tissue strength and elasticity.
Elastin (20% of total product) – A protein that supports skin, cardiovascular, cartilage, and spinal health. As its name implies, elastin gives tissue its elasticity and the ability to resume its shape after stretching.
Desmosine and isodesmosine – Two virtually unknown amino acids responsible for elastin’s elastic or rubbery properties.
Glycosaminoglycans (GAGs) – Small amounts of glucosamine, chondroitin, and hyaluronic acid – vital polysaccharides that are structural components of your connective tissue, interstitial fluids, and skeletal structure.
Transforming growth factor-b - A protein that supports tissue rejuvenation, cellular differentiation, and immune function.
Elastin (20% of total product) – A protein that supports skin, cardiovascular, cartilage, and spinal health. As its name implies, elastin gives tissue its elasticity and the ability to resume its shape after stretching.
Desmosine and isodesmosine – Two virtually unknown amino acids responsible for elastin’s elastic or rubbery properties.
Glycosaminoglycans (GAGs) – Small amounts of glucosamine, chondroitin, and hyaluronic acid – vital polysaccharides that are structural components of your connective tissue, interstitial fluids, and skeletal structure.
Transforming growth factor-b - A protein that supports tissue rejuvenation, cellular differentiation, and immune function.
Eggshell Membrane and Pain Relief –
The BiovaFlex®
Egg Membrane Advantage
Pain is one of the most frequently mentioned words in the offices of North American medical centers.
Among the chronic pain conditions, joint pain is exceedingly common. This runs the gamut from joint discomfort experienced by active “weekend warriors” to the overwhelming number of North Americans living with Osteoarthritis (OA). In fact, Osteoarthritis, which typically sets its course in those 40+ will be experienced by 1/3 of those 65 years or older, and by almost everyone in their 70s.
With good reason many consumers are interested in natural health product solutions to address joint pain, and Egg Membrane (EM) represents one of the most effective natural health products used for joint care. EM is a mesh-like material that sits between the hard shell and the egg white. It acts like a shock absorber, much like the way cartilage works in our own joints. Indeed, the egg membrane is a rich source of collagen structures, and the small protein units (peptides) that are found in our own joints.
Research involving egg membrane showed that it can reduce the pain of general joint discomfort by 73%. In the placebo-controlled trial involving patients with Osteoarthritis of the knee, EM supplementation significantly reduced pain. The researchers concluded that an individual taking EM would be 5 times more likely to experience a 50% improvement in pain compared to glucosamine. Additional clinical research continues to support EM as an effective joint care supplement.
Scientists have made some strides in understanding “how” and “why” EM works. As much as the constituents of EM might resemble those in human cartilage, it would be impossible to rebuild and restore lost or damaged cartilage in just a matter of days. It turns out that EM has strong anti-inflammatory properties. Health Canada allows for the claim “helps to reduce blood C reactive protein levels, a clinical marker of inflammation” for BiovaFlex® Egg Membrane.
Unlike other Egg Membrane products that have been effective in about 7 days, there is a more rapid response to BiovaFlex® Egg Membrane – with a clinical reduction in pain noted in just 5 days. This may be due to its high concentration of water-soluble bioactive peptides, collagen, elastin, desmosine, isodesmosine, glycosaminoglycans, and transforming growth factor. Some of these constituents may dampen pain signalling.
Importantly, the water-soluble bioactive peptides found in BiovaFlex® Egg Membrane (500mg per sachet of which are featured in our Mobile and Flexible All-In-One Joint Health Formula TM nutritional supplement) – have been shown to positively influence quality of life.
Reducing pain should translate into a return to normal, enjoyable activities! Researchers concluded that “daily consumption of 500mg water-soluble/hydrolyzed, elastin-rich BiovaFlex® Egg Membrane was associated with improved joint function, comfort during daily activities and increased physical activity”. Put simply, the study participants could once again do whatever they loved doing – in only 5 days!
And last but not least, the consumer should know that BiovaFlex® Egg Membrane is the only egg membrane product with a market-leading uniform Protein profile of 88%.
Among the chronic pain conditions, joint pain is exceedingly common. This runs the gamut from joint discomfort experienced by active “weekend warriors” to the overwhelming number of North Americans living with Osteoarthritis (OA). In fact, Osteoarthritis, which typically sets its course in those 40+ will be experienced by 1/3 of those 65 years or older, and by almost everyone in their 70s.
With good reason many consumers are interested in natural health product solutions to address joint pain, and Egg Membrane (EM) represents one of the most effective natural health products used for joint care. EM is a mesh-like material that sits between the hard shell and the egg white. It acts like a shock absorber, much like the way cartilage works in our own joints. Indeed, the egg membrane is a rich source of collagen structures, and the small protein units (peptides) that are found in our own joints.
Research involving egg membrane showed that it can reduce the pain of general joint discomfort by 73%. In the placebo-controlled trial involving patients with Osteoarthritis of the knee, EM supplementation significantly reduced pain. The researchers concluded that an individual taking EM would be 5 times more likely to experience a 50% improvement in pain compared to glucosamine. Additional clinical research continues to support EM as an effective joint care supplement.
Scientists have made some strides in understanding “how” and “why” EM works. As much as the constituents of EM might resemble those in human cartilage, it would be impossible to rebuild and restore lost or damaged cartilage in just a matter of days. It turns out that EM has strong anti-inflammatory properties. Health Canada allows for the claim “helps to reduce blood C reactive protein levels, a clinical marker of inflammation” for BiovaFlex® Egg Membrane.
Unlike other Egg Membrane products that have been effective in about 7 days, there is a more rapid response to BiovaFlex® Egg Membrane – with a clinical reduction in pain noted in just 5 days. This may be due to its high concentration of water-soluble bioactive peptides, collagen, elastin, desmosine, isodesmosine, glycosaminoglycans, and transforming growth factor. Some of these constituents may dampen pain signalling.
Importantly, the water-soluble bioactive peptides found in BiovaFlex® Egg Membrane (500mg per sachet of which are featured in our Mobile and Flexible All-In-One Joint Health Formula TM nutritional supplement) – have been shown to positively influence quality of life.
Reducing pain should translate into a return to normal, enjoyable activities! Researchers concluded that “daily consumption of 500mg water-soluble/hydrolyzed, elastin-rich BiovaFlex® Egg Membrane was associated with improved joint function, comfort during daily activities and increased physical activity”. Put simply, the study participants could once again do whatever they loved doing – in only 5 days!
And last but not least, the consumer should know that BiovaFlex® Egg Membrane is the only egg membrane product with a market-leading uniform Protein profile of 88%.
*ExceptionHYAL®
Pure Sodium Hyaluronate
(The potent Sodium Salt of Hyaluronic Acid)
If you take a look at the illustration ‘Normal Joint Structure’ that appears on this handbook, you’ll notice that our joints (like the elbows and knees) are surrounded by a membrane called the Synovial Membrane which forms a Capsule around the ends of the two articulating bones. This membrane secretes a liquid called the Synovial Fluid, and the normal viscosity of Synovial Fluid (which lubrication properties reduce damaging friction between bone ends - by keeping them apart)- is due to Hyaluronic Acid.
Synovial fluid is a viscous fluid with the consistency of motor oil. It has many functions, but none more than providing the elastic shock absorbing properties of the joint (thus aiding in the mechanical function of joints by lubrication of the articulating surfaces). Its second most important function in the joint is to carry nutrients to the Articular Cartilage (by acting as a transport medium for nutritional substances, such as glucose), and to also remove waste from the joint capsule.
The major difference between synovial fluid and other body fluids derived from plasma is the high content of Hyaluronic Acid (mucin) in synovial fluid.
An intense physical activity can lead to functional and joint overload (“stress”), whose symptoms may be joint discomfort and pain. Among the main substances that support the strength and elasticity of the musculoskeletal system, there is Hyaluronic Acid (HA). It is an organic essential component of the tendon and ligament connective tissues and of the synovial fluid that lubricates the joints and makes them functional. Unfortunately, due to ageing and functional overuse caused by physical activity, the body tends to lose HA. All this results in a gradual decreased joint and tendon efficiency and flexibility.
In these cases, we recommend a targeted and specific supplementation with a natural Chondroprotective substance, such as Sodium Hyaluronate.
Sodium hyaluronate is the salt of Hyaluronic Acid, a glycosaminoglycan (GAG) which is naturally produced in the human body and found in various connective tissue of humans. It is similar to the fluid that surrounds the joints in your body, which acts as a lubricant and shock absorber for the joints..It is used to treat knee pain caused by osteoarthritis.
The quality ingredient - ExceptionHYAL® Pure Sodium Hyaluronate - that we utilize for promoting the production of Synovial Fluid for enhancing joint (articular) structure health in our proprietary Mobile and Flexible All-In-One Joint Health Formula TM formulation - is obtained through biofermentation technology, which allows for standardization of its small molecular size and ensures quality and safety. It also has a slow and long lasting absorption at the intestinal level.
Synovial fluid is a viscous fluid with the consistency of motor oil. It has many functions, but none more than providing the elastic shock absorbing properties of the joint (thus aiding in the mechanical function of joints by lubrication of the articulating surfaces). Its second most important function in the joint is to carry nutrients to the Articular Cartilage (by acting as a transport medium for nutritional substances, such as glucose), and to also remove waste from the joint capsule.
The major difference between synovial fluid and other body fluids derived from plasma is the high content of Hyaluronic Acid (mucin) in synovial fluid.
An intense physical activity can lead to functional and joint overload (“stress”), whose symptoms may be joint discomfort and pain. Among the main substances that support the strength and elasticity of the musculoskeletal system, there is Hyaluronic Acid (HA). It is an organic essential component of the tendon and ligament connective tissues and of the synovial fluid that lubricates the joints and makes them functional. Unfortunately, due to ageing and functional overuse caused by physical activity, the body tends to lose HA. All this results in a gradual decreased joint and tendon efficiency and flexibility.
In these cases, we recommend a targeted and specific supplementation with a natural Chondroprotective substance, such as Sodium Hyaluronate.
Sodium hyaluronate is the salt of Hyaluronic Acid, a glycosaminoglycan (GAG) which is naturally produced in the human body and found in various connective tissue of humans. It is similar to the fluid that surrounds the joints in your body, which acts as a lubricant and shock absorber for the joints..It is used to treat knee pain caused by osteoarthritis.
The quality ingredient - ExceptionHYAL® Pure Sodium Hyaluronate - that we utilize for promoting the production of Synovial Fluid for enhancing joint (articular) structure health in our proprietary Mobile and Flexible All-In-One Joint Health Formula TM formulation - is obtained through biofermentation technology, which allows for standardization of its small molecular size and ensures quality and safety. It also has a slow and long lasting absorption at the intestinal level.
How does ExceptionHYAL®
Pure Sodium Hyaluronate
(potent form of Hyaluronic Acid) benefit our Joints ?
As the normal viscosity of Synovial Fluid is due to Hyaluronic Acid, ExceptionHYAL®Pure Sodium Hyaluronate improves regeneration of endogenous Synovial Fluid and promotes a healing and film-forming effect, acting like a shock absorber by lubricating and plumping tissues, helping a cushion effect and reducing inflammation.
If we compare the joints of the human body to an automobile engine, the joint fluid in the body mimics the oil in a car engine. At regular intervals we replace the oil in our car engine because the heat and friction breakdowns its motor oil viscosity. The oil becomes thinner and less able to protect the metal surfaces from excessive wear. Hyaluronic Acid (HA) benefits our joints in the same way. As we age the viscosity of the joint fluid lessens, thus HA helps to maintain normal joint cushioning.
If we compare the joints of the human body to an automobile engine, the joint fluid in the body mimics the oil in a car engine. At regular intervals we replace the oil in our car engine because the heat and friction breakdowns its motor oil viscosity. The oil becomes thinner and less able to protect the metal surfaces from excessive wear. Hyaluronic Acid (HA) benefits our joints in the same way. As we age the viscosity of the joint fluid lessens, thus HA helps to maintain normal joint cushioning.
*TURMERIC
(Curcuma longa)
(Longvida® SD Optimized Curcumin)
This extraordinary Ayurvedic herb has found its way into the spotlight in the West because of its wide range of health benefits.
Turmeric is a potent antioxidant. Curcumin, its main active constituent, is as powerful an antioxidant as vitamins C, E and Beta-Carotene, making turmeric usage a consumer choice for liver disease protection, premature aging prevention, and brain health enhancement.
In addition, Turmeric induces Glutathione biosynthesis and is a powerful anti-inflammatory, easing conditions such as bursitis, arthritis and back pain. Turmeric’s anti-inflammatory action is likely due to a combination of three different properties. First, turmeric lowers the production of inflammation-inducing histamine. Secondly, it increases and prolongs the action of the body’s natural anti-inflammatory adrenal hormone, cortisol, and finally, turmeric improves circulation, thereby flushing toxins out of small joints where cellular wastes and inflammatory compounds are frequently trapped.
Research has also confirmed the digestive benefits of Turmeric. Turmeric acts as a cholagogue, stimulating bile production, thus, increasing the bodies’ ability to digest fats, improving digestion and eliminating toxins from the liver. Turmeric has also displayed anti-ulcer activity. By reducing the amount of acid secreted, it helps to protect the lining of the stomach where peptic ulcers occur.
Since one of the problems in curcumin absorption is that it gets broken down in the stomach quickly, we exclusively use Longvida® SD Optimized Curcumin in our formulation as it encapsulates curcumin to protect it from hydrolysis. This patented technology is called SLCP technology – Solid Lipid Curcumin Particle Technology. Through this technology, curcumin is protected from the acid in the stomach, so it gets dissolved in the point of absorption, which is the GI Tract. The end result is that higher levels of curcumin get to the target tissues.
Longvida® SD Optimized Curcumin aims to get as much free curcumin into the blood and tissues as possible. This formulation does not contain any turmeric oils, only curcumin. Experts have tested the effectiveness of Longvida compared to ordinary curcumin. In human studies, they found out that Longvida® SD Optimized Curcumin is 65 times more bioavailable based on maximum concentration in blood plasma, and is 100 times more bioavailable based on AUC or Area Under the Curve.
Longvida® SD was formulated by UCLA neuroscientists and Verdure Sciences. It focuses on curcumin’s ability to support neurogenesis, which is the regeneration of brain cells. Curcumin has been proven to increase the levels of BDNF (Brain-Derived Neurotrophic Factor) in the brain. BDNF is a type of hormone in the brain. As we grow older, the amount of BDNF in the brain drops, and this contributes to diseases like dementia and Alzheimer’s disease. Curcumin helps prevent these diseases by increasing the amount of BDNF in the brain.
Longvida® SD also takes advantage of curcumin’s antioxidant and anti-inflammatory properties to protect brain cells. Some brain diseases, such as Alzheimer’s disease, may be caused by amyloid-B protein fragments in the brain that cause Oxidative Stress and inflammation. Curcumin effectively binds with these fragments, which helps stop them from causing plaque between neurons, thus, helping prevent the onset of some brain diseases. In Longvida® SD’s formulation, the brain benefits a lot from curcumin’s antioxidant and anti-inflammatory properties.
Longvida® SD is the form (liposomal encapsulation) of Curcumin that works best for adverse health brain conditions . It is formulated to cross the blood-brain barrier, so it’s most effective for diseases like dementia, cognitive impairment, and Alzheimer’s disease.
Turmeric is a potent antioxidant. Curcumin, its main active constituent, is as powerful an antioxidant as vitamins C, E and Beta-Carotene, making turmeric usage a consumer choice for liver disease protection, premature aging prevention, and brain health enhancement.
In addition, Turmeric induces Glutathione biosynthesis and is a powerful anti-inflammatory, easing conditions such as bursitis, arthritis and back pain. Turmeric’s anti-inflammatory action is likely due to a combination of three different properties. First, turmeric lowers the production of inflammation-inducing histamine. Secondly, it increases and prolongs the action of the body’s natural anti-inflammatory adrenal hormone, cortisol, and finally, turmeric improves circulation, thereby flushing toxins out of small joints where cellular wastes and inflammatory compounds are frequently trapped.
Research has also confirmed the digestive benefits of Turmeric. Turmeric acts as a cholagogue, stimulating bile production, thus, increasing the bodies’ ability to digest fats, improving digestion and eliminating toxins from the liver. Turmeric has also displayed anti-ulcer activity. By reducing the amount of acid secreted, it helps to protect the lining of the stomach where peptic ulcers occur.
Since one of the problems in curcumin absorption is that it gets broken down in the stomach quickly, we exclusively use Longvida® SD Optimized Curcumin in our formulation as it encapsulates curcumin to protect it from hydrolysis. This patented technology is called SLCP technology – Solid Lipid Curcumin Particle Technology. Through this technology, curcumin is protected from the acid in the stomach, so it gets dissolved in the point of absorption, which is the GI Tract. The end result is that higher levels of curcumin get to the target tissues.
Longvida® SD Optimized Curcumin aims to get as much free curcumin into the blood and tissues as possible. This formulation does not contain any turmeric oils, only curcumin. Experts have tested the effectiveness of Longvida compared to ordinary curcumin. In human studies, they found out that Longvida® SD Optimized Curcumin is 65 times more bioavailable based on maximum concentration in blood plasma, and is 100 times more bioavailable based on AUC or Area Under the Curve.
Longvida® SD was formulated by UCLA neuroscientists and Verdure Sciences. It focuses on curcumin’s ability to support neurogenesis, which is the regeneration of brain cells. Curcumin has been proven to increase the levels of BDNF (Brain-Derived Neurotrophic Factor) in the brain. BDNF is a type of hormone in the brain. As we grow older, the amount of BDNF in the brain drops, and this contributes to diseases like dementia and Alzheimer’s disease. Curcumin helps prevent these diseases by increasing the amount of BDNF in the brain.
Longvida® SD also takes advantage of curcumin’s antioxidant and anti-inflammatory properties to protect brain cells. Some brain diseases, such as Alzheimer’s disease, may be caused by amyloid-B protein fragments in the brain that cause Oxidative Stress and inflammation. Curcumin effectively binds with these fragments, which helps stop them from causing plaque between neurons, thus, helping prevent the onset of some brain diseases. In Longvida® SD’s formulation, the brain benefits a lot from curcumin’s antioxidant and anti-inflammatory properties.
Longvida® SD is the form (liposomal encapsulation) of Curcumin that works best for adverse health brain conditions . It is formulated to cross the blood-brain barrier, so it’s most effective for diseases like dementia, cognitive impairment, and Alzheimer’s disease.
*BOSWELLIA SERRATA
Boswellia is a herbal extract taken from the Boswellia serrata tree. The gummy exudate or the resin obtained by peeling away the bark is commonly known as Indian frankincense. It has been used widely for centuries in Ayurvedic medicine for treating Arthritis among other health conditions.
Numerous clinical studies have shown the capacity of Boswellia serrata (via its active components called Boswellic Acids) to diminish symptoms of adverse joint health conditions, such as Osteoarthritis (OA) - by helping to decrease pain, swelling, and stiffness, as well as by providing support to joint function. Research has also shown that Boswellia serrata may increase knee flexion and walking distance while reducing pain in people with Knee Osteoarthritis.
Boswellia Serrata, via one of its active Boswellic Acids, called AKBA, (perhaps the most active component of Boswellia) has been demonstrated to be a potent inhibitor of 5-lipoxygenase, a key enzyme in the biosynthesis of Leukotrienes from arachidonic acid in the cellular inflammatory cascade. It may also possess other anti-inflammatory effects (such as nF-kB inhibition).
These anti-inflammatory effects have been investigated for their benefits in Osteoarthritis (OA), and it appears that oral Boswellia supplements can suppress pain and lack of mobility associated with OA quite significantly, with the effects taking little time to occur.
Besides being an effective anti-inflammatory, some studies demonstrate that Boswellia can be an effective natural analgesic (pain reliever), and may also prevent the deterioration (thinning) of Articular (joint) Cartilage.
Numerous clinical studies have shown the capacity of Boswellia serrata (via its active components called Boswellic Acids) to diminish symptoms of adverse joint health conditions, such as Osteoarthritis (OA) - by helping to decrease pain, swelling, and stiffness, as well as by providing support to joint function. Research has also shown that Boswellia serrata may increase knee flexion and walking distance while reducing pain in people with Knee Osteoarthritis.
Boswellia Serrata, via one of its active Boswellic Acids, called AKBA, (perhaps the most active component of Boswellia) has been demonstrated to be a potent inhibitor of 5-lipoxygenase, a key enzyme in the biosynthesis of Leukotrienes from arachidonic acid in the cellular inflammatory cascade. It may also possess other anti-inflammatory effects (such as nF-kB inhibition).
These anti-inflammatory effects have been investigated for their benefits in Osteoarthritis (OA), and it appears that oral Boswellia supplements can suppress pain and lack of mobility associated with OA quite significantly, with the effects taking little time to occur.
Besides being an effective anti-inflammatory, some studies demonstrate that Boswellia can be an effective natural analgesic (pain reliever), and may also prevent the deterioration (thinning) of Articular (joint) Cartilage.
*MONTMORENCY TART CHERRY POWDER
Montmorency tart cherries (Prunus cerasus) are now more commonly lauded for their health benefits than their culinary prowess, as extensive research has put tart cherries at the top of the superfruit totem pole .
Numerous universities and research institutions have conducted studies regarding this cherry variety in the areas of muscle recovery, gout, inflammation and sleep (via naturally occurring Melatonin). They may naturally help the body increase its level of Melatonin, an important hormone that naturally occurs in the brain (it is made in the pineal gland), which besides been directly linked to improved sleep, is also a major precursor of Glutathione at the cellular level.
Additionally, Melatonin functions as an antioxidant, and Montmorency tart cherry is one of its principal natural food sources.
In terms of its promising health benefits for athletes and sports recovery to help relieve muscle and joint soreness, results from one of the Tart Cherry studies conducted at a Texas university (on acute Endurance exercise performance in aerobically trained individuals) revealed that short-term supplementation of Montmorency powdered tart cherries surrounding an endurance challenge attenuated markers of muscle catabolism, reduced immune and inflammatory stress, better maintained redox balance, and increased performance in aerobically trained individuals. Meanwhile, another study at that same university (on an acute bout of intense lower body strength exercise in Resistance trained males) concluded that short-term supplementation of Montmorency powdered tart cherries appears to be an effective dietary supplement to attenuate muscle soreness, strength decrement during recovery, and markers of muscle catabolism in resistance-trained individuals.
Published scientific studies also show that Montmorency tart cherries abundantly contain unique Anthocyanins - one of Nature’s most potent classes of flavonoids - and other compounds that naturally may help mediate the inflammatory process, including nutritionally-supporting the body to reduce inflammation and ease the pain of osteoarthritis and gout, one of the most painful arthritic manifestations. Anthocyanins are powerful nutrients responsible for the deep colors in some berries, fruits, and vegetables, and anthocyanin-rich foods, such as tart cherries deliver substantial antioxidant and anti-inflammatory act.
Tart cherries contain 19 times more beta-carotene than blueberries, and strawberries. In addition, they are a source of vitamin C, potassium, magnesium, iron and folate, as well as of other phenolic compounds, such as gallic acid, p-coumaric acid, kaempferol, and quercetin, all of which are potent antioxidants.
Regarding Montmorency Tart Cherry’s health-benefiting, nutritionally-supporting impact that may help patients suffering Gout, one of the most painful arthritic conditions, we’ll like to share information that in a 2003 study, 280 grams of cherries (about 45 cherries) was given to 10 healthy women. Blood uric acid levels decreased by 14% after 5 hours and excretion of uric acid increased. CRP levels also decreased slightly (Jacob RA, et al. J Nutr 2003;133:1826–9).
Also in a 2011 randomized, placebo-controlled crossover study, 10 participants consumed 8 oz/day of either 100% tart cherry juice or placebo beverage for 4 weeks, with a 2-week washout period between switching treatments. Although participants had normal uric acid levels, 7/10 participants displayed reduced serum uric acid levels after tart cherry juice consumption. The erythrocyte sedimentation rate (ESR), an indicator of inflammation, was significantly lower with tart cherry juice treatment versus placebo (Martin KR, et al. FASEB 2011;25;339.2).
Research studies from the University of Michigan have also demonstrated that Tart Cherry consumption has been linked to a number of important cardiovascular benefits — from overall anti-inflammation to reductions in bad cholesterol levels, to decreased risk for atherosclerosis and for the Metabolic Syndrome - all important heart disease risk factors.
And last but not least, researchers continue to uncover new and novel benefits of tart cherries. Some preliminary research has linked tart cherry juice to improvements in sleep and sleep patterns. In one pilot study, a team of University of Pennsylvania, University of Rochester and VA Center of Canandaigua researchers found that drinking tart cherry juice daily helped reduce the severity of insomnia and time spent awake after going to sleep. The 15 older adults saved about 17 minutes of wake time after going to sleep, on average, when drinking cherry juice daily, compared to when they were drinking the juice drink. A second study found that healthy adults experienced improved sleep time and a 5-6 percent increase in overall sleep efficiency after drinking two servings of tart cherry juice for a week, compared to drinking a fruit cocktail. The volunteers also reported less daytime napping time while drinking the tart cherry juice.
Numerous universities and research institutions have conducted studies regarding this cherry variety in the areas of muscle recovery, gout, inflammation and sleep (via naturally occurring Melatonin). They may naturally help the body increase its level of Melatonin, an important hormone that naturally occurs in the brain (it is made in the pineal gland), which besides been directly linked to improved sleep, is also a major precursor of Glutathione at the cellular level.
Additionally, Melatonin functions as an antioxidant, and Montmorency tart cherry is one of its principal natural food sources.
In terms of its promising health benefits for athletes and sports recovery to help relieve muscle and joint soreness, results from one of the Tart Cherry studies conducted at a Texas university (on acute Endurance exercise performance in aerobically trained individuals) revealed that short-term supplementation of Montmorency powdered tart cherries surrounding an endurance challenge attenuated markers of muscle catabolism, reduced immune and inflammatory stress, better maintained redox balance, and increased performance in aerobically trained individuals. Meanwhile, another study at that same university (on an acute bout of intense lower body strength exercise in Resistance trained males) concluded that short-term supplementation of Montmorency powdered tart cherries appears to be an effective dietary supplement to attenuate muscle soreness, strength decrement during recovery, and markers of muscle catabolism in resistance-trained individuals.
Published scientific studies also show that Montmorency tart cherries abundantly contain unique Anthocyanins - one of Nature’s most potent classes of flavonoids - and other compounds that naturally may help mediate the inflammatory process, including nutritionally-supporting the body to reduce inflammation and ease the pain of osteoarthritis and gout, one of the most painful arthritic manifestations. Anthocyanins are powerful nutrients responsible for the deep colors in some berries, fruits, and vegetables, and anthocyanin-rich foods, such as tart cherries deliver substantial antioxidant and anti-inflammatory act.
Tart cherries contain 19 times more beta-carotene than blueberries, and strawberries. In addition, they are a source of vitamin C, potassium, magnesium, iron and folate, as well as of other phenolic compounds, such as gallic acid, p-coumaric acid, kaempferol, and quercetin, all of which are potent antioxidants.
Regarding Montmorency Tart Cherry’s health-benefiting, nutritionally-supporting impact that may help patients suffering Gout, one of the most painful arthritic conditions, we’ll like to share information that in a 2003 study, 280 grams of cherries (about 45 cherries) was given to 10 healthy women. Blood uric acid levels decreased by 14% after 5 hours and excretion of uric acid increased. CRP levels also decreased slightly (Jacob RA, et al. J Nutr 2003;133:1826–9).
Also in a 2011 randomized, placebo-controlled crossover study, 10 participants consumed 8 oz/day of either 100% tart cherry juice or placebo beverage for 4 weeks, with a 2-week washout period between switching treatments. Although participants had normal uric acid levels, 7/10 participants displayed reduced serum uric acid levels after tart cherry juice consumption. The erythrocyte sedimentation rate (ESR), an indicator of inflammation, was significantly lower with tart cherry juice treatment versus placebo (Martin KR, et al. FASEB 2011;25;339.2).
Research studies from the University of Michigan have also demonstrated that Tart Cherry consumption has been linked to a number of important cardiovascular benefits — from overall anti-inflammation to reductions in bad cholesterol levels, to decreased risk for atherosclerosis and for the Metabolic Syndrome - all important heart disease risk factors.
And last but not least, researchers continue to uncover new and novel benefits of tart cherries. Some preliminary research has linked tart cherry juice to improvements in sleep and sleep patterns. In one pilot study, a team of University of Pennsylvania, University of Rochester and VA Center of Canandaigua researchers found that drinking tart cherry juice daily helped reduce the severity of insomnia and time spent awake after going to sleep. The 15 older adults saved about 17 minutes of wake time after going to sleep, on average, when drinking cherry juice daily, compared to when they were drinking the juice drink. A second study found that healthy adults experienced improved sleep time and a 5-6 percent increase in overall sleep efficiency after drinking two servings of tart cherry juice for a week, compared to drinking a fruit cocktail. The volunteers also reported less daytime napping time while drinking the tart cherry juice.
*MAGNESIUM MALATE
We utilize Magnesium Malate in our formulation. It is a combination of Magnesium fortified with Malic Acid, which may be beneficial for pain relief, fatigue, constipation, or a variety of other muscular, metabolic, and physical imbalances.
This powder (also known as magnesium salt with malic acid) is also noted for soothing muscles and speeding recovery time after extended workouts or training.
Studies have shown that only about 25% of U.S. adults are at or above the recommended daily amount of 310 to 320 milligrams for women and 400 to 420 milligrams for men. In fact, more than a decade ago, the 2005-2006 National Health and Nutrition Examination Survey (NHANES) revealed that at least half (50%) of the U.S. population had inadequate intakes of Magnesium.
But no matter what the real percentage may presently be, it’s a fact that a large portion of the population could be facing a Magnesium deficiency.
Magnesium is an essential mineral that is required by virtually every cell, and it’s an essential co-factor in more than 300 biochemical (enzymatic) reactions in the body that sustain and regulate basic human health and function - including the liver enzyme responsible for converting vitamin D to its active form. Some of these hundreds of processes include : muscle contraction and relaxation, nerve function, cardiac activity, blood pressure regulation, hormonal interactions, immunity, bone health and the metabolism of proteins, fats and nucleic acids, among many others.
Its excellent healthy effects may be based on how it facilitates the body's use of oxygen. Magnesium is to plant chlorophyll as iron is to human hemoglobin. In our body, magnesium-rich chlorophyll supplies the means to drive our mitochondrial pump, creating life-giving energy. This means magnesium provides oxygen to our muscles, making it a most important nutrient for athletes and non-athletes alike.
Glutathione, the body’s premier antioxidant, could not be produced without Magnesium, as this mineral plays a vital role in its synthesis via the proper functioning of the enzyme Gamma Glutamyl Transpeptidase (GGT), which is the only enzyme located on the outside of plasma cell membranes, where it breaks down circulating extracellular Glutathione and releases the all-important amino acid Cysteine for the intracellular re-assembling of Glutathione.
This means that GGT is involved in Cysteine delivery to tissues demanding it at the moment in response to Oxidative Stress or a pathogen. (Gamma-glutamyl transpeptidase in Glutathione biosynthesis. Zhang H et al. Methods Enzymol. 2005;401:468-83.)
Magnesium also stimulates the hormone Calcitonin, which helps support healthy bone structure by drawing calcium out of the blood and tissues and back into the bones. It also plays a key role in the production of Adenosine TriPhosphate (ATP)… the body’s master energy molecule, as this mineral is crucial for cellular respiration (or energy metabolism) by the activation of enzymes known as ATPases, which are needed to generate it.
When ATP is broken down, energy is released for all muscle contractions, and when exercising strenuously, this turnover is extremely high, meaning that ATP needs to be synthesized quickly. Thus a shortfall of Magnesium can limit energy production, leading to fatigue, lethargy, reduced power, muscle twitches or cramps.
Magnesium plays a structural role in bones, cell membranes, and chromosomes. It’s required for the active transport of other metal ions across cell membranes, thus affecting nerve transmission, muscle contraction, and heart rhythm. And it’s also required for many cell-signaling functions (the conveyance of chemical messages within and between cells).
Malic acid, on the other hand, is a substance found in our body, which is a key component (along with magnesium, oxygen, & B-vitamins) to create energy, as it helps create the all-important ATP molecule of cellular energy even under low oxygen conditions. As a supplement, Malic acid is found in fruits, especially apples (as a matter of fact, in Latin, “malium” means apple).
This powder (also known as magnesium salt with malic acid) is also noted for soothing muscles and speeding recovery time after extended workouts or training.
Studies have shown that only about 25% of U.S. adults are at or above the recommended daily amount of 310 to 320 milligrams for women and 400 to 420 milligrams for men. In fact, more than a decade ago, the 2005-2006 National Health and Nutrition Examination Survey (NHANES) revealed that at least half (50%) of the U.S. population had inadequate intakes of Magnesium.
But no matter what the real percentage may presently be, it’s a fact that a large portion of the population could be facing a Magnesium deficiency.
Magnesium is an essential mineral that is required by virtually every cell, and it’s an essential co-factor in more than 300 biochemical (enzymatic) reactions in the body that sustain and regulate basic human health and function - including the liver enzyme responsible for converting vitamin D to its active form. Some of these hundreds of processes include : muscle contraction and relaxation, nerve function, cardiac activity, blood pressure regulation, hormonal interactions, immunity, bone health and the metabolism of proteins, fats and nucleic acids, among many others.
Its excellent healthy effects may be based on how it facilitates the body's use of oxygen. Magnesium is to plant chlorophyll as iron is to human hemoglobin. In our body, magnesium-rich chlorophyll supplies the means to drive our mitochondrial pump, creating life-giving energy. This means magnesium provides oxygen to our muscles, making it a most important nutrient for athletes and non-athletes alike.
Glutathione, the body’s premier antioxidant, could not be produced without Magnesium, as this mineral plays a vital role in its synthesis via the proper functioning of the enzyme Gamma Glutamyl Transpeptidase (GGT), which is the only enzyme located on the outside of plasma cell membranes, where it breaks down circulating extracellular Glutathione and releases the all-important amino acid Cysteine for the intracellular re-assembling of Glutathione.
This means that GGT is involved in Cysteine delivery to tissues demanding it at the moment in response to Oxidative Stress or a pathogen. (Gamma-glutamyl transpeptidase in Glutathione biosynthesis. Zhang H et al. Methods Enzymol. 2005;401:468-83.)
Magnesium also stimulates the hormone Calcitonin, which helps support healthy bone structure by drawing calcium out of the blood and tissues and back into the bones. It also plays a key role in the production of Adenosine TriPhosphate (ATP)… the body’s master energy molecule, as this mineral is crucial for cellular respiration (or energy metabolism) by the activation of enzymes known as ATPases, which are needed to generate it.
When ATP is broken down, energy is released for all muscle contractions, and when exercising strenuously, this turnover is extremely high, meaning that ATP needs to be synthesized quickly. Thus a shortfall of Magnesium can limit energy production, leading to fatigue, lethargy, reduced power, muscle twitches or cramps.
Magnesium plays a structural role in bones, cell membranes, and chromosomes. It’s required for the active transport of other metal ions across cell membranes, thus affecting nerve transmission, muscle contraction, and heart rhythm. And it’s also required for many cell-signaling functions (the conveyance of chemical messages within and between cells).
Malic acid, on the other hand, is a substance found in our body, which is a key component (along with magnesium, oxygen, & B-vitamins) to create energy, as it helps create the all-important ATP molecule of cellular energy even under low oxygen conditions. As a supplement, Malic acid is found in fruits, especially apples (as a matter of fact, in Latin, “malium” means apple).
For Athletes
Magnesium plays a pivotal role in energy production, thus making it a must for athletic performance.
Athletes in particular might find it easy to explain away fatigue or muscle cramps, lowered immunity, and even altered heart rates, and indeed these symptoms are common and multi-faceted in cause. However, a simple Magnesium deficiency could also be the underlying factor.
There is emerging evidence that Magnesium requirements are significantly elevated in Athletes, and that performance might benefit from higher intakes. Aside from being used up in the production of energy, magnesium might also assist performance by reducing accumulation of lactic acid and reducing the perception of fatigue during strenuous exercise through its action on the nervous system. Overworked muscles produce free radicals, and magnesium aids in the production of Glutathione, that besides been the body’s master antioxidant and detoxifier, also enhances performance, prevents lactic acid build-up, and shortens recovery time.
In Athletes, Magnesium deficiency is often found in the Overtraining Syndrome (its various signs and symptoms), which can result in hormonal, nutritional, mental/emotional, muscular, neurological and other imbalances. These, in turn, can cause fatigue, depression, injuries and poor performance to name a few problems. If muscles are deficient in magnesium, they become irritated and on edge developing tics, twitches, and outright spasms or "charley horses" as they are known when they occur in our calves. If you are feeling generally irritated and on edge, magnesium deficiency may be the cause. If not counteract with dynamic nutritional support to enhance Glutathione antioxidant production at the cellular level, this situation may well contribute to the development of Oxidative Stress (with its dreadful consequences) in the individual.
Magnesium is also lost through sweat, so athletes training hard in hot and humid environments might further increase demands. Research suggests that endurance athletes can safely consume 500 to 800 mg daily, and there is debate as to whether this amount should be higher still.
Athletes in particular might find it easy to explain away fatigue or muscle cramps, lowered immunity, and even altered heart rates, and indeed these symptoms are common and multi-faceted in cause. However, a simple Magnesium deficiency could also be the underlying factor.
There is emerging evidence that Magnesium requirements are significantly elevated in Athletes, and that performance might benefit from higher intakes. Aside from being used up in the production of energy, magnesium might also assist performance by reducing accumulation of lactic acid and reducing the perception of fatigue during strenuous exercise through its action on the nervous system. Overworked muscles produce free radicals, and magnesium aids in the production of Glutathione, that besides been the body’s master antioxidant and detoxifier, also enhances performance, prevents lactic acid build-up, and shortens recovery time.
In Athletes, Magnesium deficiency is often found in the Overtraining Syndrome (its various signs and symptoms), which can result in hormonal, nutritional, mental/emotional, muscular, neurological and other imbalances. These, in turn, can cause fatigue, depression, injuries and poor performance to name a few problems. If muscles are deficient in magnesium, they become irritated and on edge developing tics, twitches, and outright spasms or "charley horses" as they are known when they occur in our calves. If you are feeling generally irritated and on edge, magnesium deficiency may be the cause. If not counteract with dynamic nutritional support to enhance Glutathione antioxidant production at the cellular level, this situation may well contribute to the development of Oxidative Stress (with its dreadful consequences) in the individual.
Magnesium is also lost through sweat, so athletes training hard in hot and humid environments might further increase demands. Research suggests that endurance athletes can safely consume 500 to 800 mg daily, and there is debate as to whether this amount should be higher still.
For Seniors
Inadequate Magnesium intake is especially common in older persons, and Sarcopenia (loss of muscle mass due to aging) as well as Dynapenia (loss of muscle strength) are prevalent conditions in older persons, and are strong, independent risk factors for frailty, disability and mortality.
Accordingly, as Magnesium nutritionally supports metabolism, energy production (ATP), and optimal cellular function, elderly persons that suffer these adverse health conditions - by supplementing with it on a daily basis - may notice greater physical and mental energy, reduced fatigue, and often a greater sense of overall well-being.
A research study published (July 2014) in the American Journal of Clinical Nutrition corroborated that Magnesium supplementation can improve physical performance in older women. It tested the effect of Magnesium on older women’s ability to carry out everyday functional movements such as lifting and carrying, alongside other measures of strength and balance. These findings suggest a role for Magnesium supplementation in preventing or delaying the age-related decline in physical performance, particularly in magnesium-deficient individuals.
Accordingly, as Magnesium nutritionally supports metabolism, energy production (ATP), and optimal cellular function, elderly persons that suffer these adverse health conditions - by supplementing with it on a daily basis - may notice greater physical and mental energy, reduced fatigue, and often a greater sense of overall well-being.
A research study published (July 2014) in the American Journal of Clinical Nutrition corroborated that Magnesium supplementation can improve physical performance in older women. It tested the effect of Magnesium on older women’s ability to carry out everyday functional movements such as lifting and carrying, alongside other measures of strength and balance. These findings suggest a role for Magnesium supplementation in preventing or delaying the age-related decline in physical performance, particularly in magnesium-deficient individuals.
*MSM (Methylsulfonylmethane)
Starting in the 1930s, researchers reported arthritis sufferers were deficient in sulfur, and that restoring sulfur levels provided significant benefits to these patients. It wasn’t until 1979, however, that Dr. Stanley Jacob, M.D. discovered MSM while doing research at Oregon Health and Sciences University in Portland Oregon. A surgeon and former instructor of surgery at Harvard Medical School, Dr. Jacob is considered the world’s foremost expert on its research and clinical applications. He has used MSM with over 18,000 patients in his practice for the last 25 years. Patients with osteoarthritis, rheumatoid arthritis, muscle soreness and muscle pain all benefited significantly from MSM.
MSM stands for Methylsulfonylmethane, an organic form of sulfur. Sulfur is the fourth most plentiful mineral in your body and is essential for life. It is an important element for all cells and body tissues, especially for joint tissue where it functions in the stabilization of the connective tissue matrix of cartilage, tendons, and ligaments. MSM is composed of 34% bio-available sulfur, making it the richest source of organic sulfur available.
Sulfur is vital to the creation and regeneration of the body's tissues. It is found in every cell in the body. Approximately half of the sulfur in your body is concentrated in the muscles, skin and bones. When rigid fibrous tissue cells swell and become inflamed, pressure and pain result. MSM restores the flexibility and permeability of cell walls allowing fluids to pass through the tissues with ease. This means that the cells can quickly get rid of garbage that is constantly being created inside the cell, and the cell can also absorb nutrients more easily. MSM is a powerful detoxifier that allows harmful substances such as lactic acid and toxins to flow out of cells in the joints and muscles, thereby equalizing the pressure and eliminating the cause of pain. This prevents the pressure buildup in cells that causes inflammation.
MSM has shown a remarkable ability to reduce or eliminate muscle soreness and cramps both in geriatric patients and in athletes. Taken along with Hydrolyzed Collagen Peptides and GAGs (Glycoaminoglycans), key substances in the process of rebuilding cartilage, MSM can help relieve pain and help repair worn or damaged cartilage in joints, ligaments and tendons with healthy, flexible new cells.
Methylsulfonylmethane (MSM) also plays an important role in the synthesis of master antioxidant Glutathione (GSH). This natural ingredient has been recently confirmed by Ohio State University researchers as an enhancer of the intracellular production of tri-peptide Gluthathione in the Liver.
Sulfur is a critically active component in the reduced (active) form of a Glutathione molecule (GSH). Sulfur is represented by “SH” (Sulfhydryl group) in the common abbreviation for Glutathione (GSH).
Additionally, MSM supplementation may help maintain Glutathione levels by helping decrease inflammation and Oxidative Stress, as well as by participating in the metabolism of Glutathione-promoting amino acids Cysteine and Methionine, and by contributing the continuous supply of Sulfur for many vital processes in the body.
MSM stands for Methylsulfonylmethane, an organic form of sulfur. Sulfur is the fourth most plentiful mineral in your body and is essential for life. It is an important element for all cells and body tissues, especially for joint tissue where it functions in the stabilization of the connective tissue matrix of cartilage, tendons, and ligaments. MSM is composed of 34% bio-available sulfur, making it the richest source of organic sulfur available.
Sulfur is vital to the creation and regeneration of the body's tissues. It is found in every cell in the body. Approximately half of the sulfur in your body is concentrated in the muscles, skin and bones. When rigid fibrous tissue cells swell and become inflamed, pressure and pain result. MSM restores the flexibility and permeability of cell walls allowing fluids to pass through the tissues with ease. This means that the cells can quickly get rid of garbage that is constantly being created inside the cell, and the cell can also absorb nutrients more easily. MSM is a powerful detoxifier that allows harmful substances such as lactic acid and toxins to flow out of cells in the joints and muscles, thereby equalizing the pressure and eliminating the cause of pain. This prevents the pressure buildup in cells that causes inflammation.
MSM has shown a remarkable ability to reduce or eliminate muscle soreness and cramps both in geriatric patients and in athletes. Taken along with Hydrolyzed Collagen Peptides and GAGs (Glycoaminoglycans), key substances in the process of rebuilding cartilage, MSM can help relieve pain and help repair worn or damaged cartilage in joints, ligaments and tendons with healthy, flexible new cells.
Methylsulfonylmethane (MSM) also plays an important role in the synthesis of master antioxidant Glutathione (GSH). This natural ingredient has been recently confirmed by Ohio State University researchers as an enhancer of the intracellular production of tri-peptide Gluthathione in the Liver.
Sulfur is a critically active component in the reduced (active) form of a Glutathione molecule (GSH). Sulfur is represented by “SH” (Sulfhydryl group) in the common abbreviation for Glutathione (GSH).
Additionally, MSM supplementation may help maintain Glutathione levels by helping decrease inflammation and Oxidative Stress, as well as by participating in the metabolism of Glutathione-promoting amino acids Cysteine and Methionine, and by contributing the continuous supply of Sulfur for many vital processes in the body.
*SILICA (Silicon dioxide)
Silica is silicon dioxide, a trace mineral found in bones, teeth, skin, eyes, glands and organs. It’s also a major constituent of Collagen.
Additionally, Silica works with Calcium to maintain bone strength.
Convincing evidence from human, animal, and in vitro studies performed by several laboratories that Silica is a bioactive beneficial trace element continues to accumulate over the last 40 years, suggesting that this trace mineral has an important role in bone formation and bone and connective tissue health, and that in addition, it may have a modulating effect on the immune or inflammatory response.
Mechanisms are unclear but evidence exists of its involvement in Collagen synthesis and/or its stabilization and in matrix mineralization. Thus, creating and maintaining Collagen is one of the most vital roles Silica plays, which is why it is a very important mineral for joint health.
Silica ensures the connection between Collagen and Proteoglycans. Proteoglycans (including Aggrecan/Chondroitin Sulfate, the major Proteoglycan in Cartilage) make links with Collagen and are major components of the space between cells. They make Collagen-rich structures more resilient and bind water for better hydration.
Proteoglycans are a major component of the extracellular matrix, the "filler" substance existing between cells in our organism. Here they form large complexes, both to other Proteoglycans, to Hyaluronan (Hyaluronic Acid), and to fibrous matrix proteins, such as Collagen. The combination of Proteoglycans and Collagen form Cartilage, a sturdy tissue that is usually heavily hydrated (mostly due to the negatively charged sulfates in the Glycosaminoglycan chains of the Proteoglycans).
A plausible mechanism of action for the beneficial effects of Silica is the binding of hydroxyl groups of polyols such that it also influences the formation and/or utilization of Glycosaminoglycans (GAGs) - such as glucosamine and chondroitin, etc. – as well as of Mucopolysaccharides, and Collagen in connective tissue and bone.
Within bone, Silica is the essential component making up the Collagen matrix upon which calcium is deposited. This relationship is so fundamental that it is truly impossible to form bone without both calcium and Silica.
In addition, Silica may positively affect the absorption, retention or action of other mineral elements (e.g., aluminum, copper, magnesium).
Additionally, Silica works with Calcium to maintain bone strength.
Convincing evidence from human, animal, and in vitro studies performed by several laboratories that Silica is a bioactive beneficial trace element continues to accumulate over the last 40 years, suggesting that this trace mineral has an important role in bone formation and bone and connective tissue health, and that in addition, it may have a modulating effect on the immune or inflammatory response.
Mechanisms are unclear but evidence exists of its involvement in Collagen synthesis and/or its stabilization and in matrix mineralization. Thus, creating and maintaining Collagen is one of the most vital roles Silica plays, which is why it is a very important mineral for joint health.
Silica ensures the connection between Collagen and Proteoglycans. Proteoglycans (including Aggrecan/Chondroitin Sulfate, the major Proteoglycan in Cartilage) make links with Collagen and are major components of the space between cells. They make Collagen-rich structures more resilient and bind water for better hydration.
Proteoglycans are a major component of the extracellular matrix, the "filler" substance existing between cells in our organism. Here they form large complexes, both to other Proteoglycans, to Hyaluronan (Hyaluronic Acid), and to fibrous matrix proteins, such as Collagen. The combination of Proteoglycans and Collagen form Cartilage, a sturdy tissue that is usually heavily hydrated (mostly due to the negatively charged sulfates in the Glycosaminoglycan chains of the Proteoglycans).
A plausible mechanism of action for the beneficial effects of Silica is the binding of hydroxyl groups of polyols such that it also influences the formation and/or utilization of Glycosaminoglycans (GAGs) - such as glucosamine and chondroitin, etc. – as well as of Mucopolysaccharides, and Collagen in connective tissue and bone.
Within bone, Silica is the essential component making up the Collagen matrix upon which calcium is deposited. This relationship is so fundamental that it is truly impossible to form bone without both calcium and Silica.
In addition, Silica may positively affect the absorption, retention or action of other mineral elements (e.g., aluminum, copper, magnesium).
*vitamin D3 (Cholecalciferol)
Vitamin D helps our bones absorb calcium, which is vital to bone health. It’s also crucial for muscle movement, communication between nerves, and fighting inflammation.
According to the Arthritis Foundation, people who take oral steroids have a vitamin D deficiency twice as often as people who don’t take them. Oral steroids are a common treatment for people with arthritis. Another study found that vitamin D deficiency is common in people with rheumatoid arthritis (RA), and may be linked to musculoskeletal pain.
Research has also found that vitamin D may play a significant role in joint health, and that low levels may increase the risk of rheumatologic conditions such as arthritis. Several studies have found low blood levels of vitamin D in patients with osteoarthritis of the hip and knee.
In another study of more than 2,000 people, researchers found that vitamin D deficiency was strongly associated with disabling symptoms among those with rheumatoid arthritis. While it may be true that people with arthritis don't get as much sun exposure — exposure to the sun helps promote vitamin D production in the body — the study authors adjusted for that and still found that being vitamin D deficient was linked to arthritis pain.
According to the Arthritis Foundation, people who take oral steroids have a vitamin D deficiency twice as often as people who don’t take them. Oral steroids are a common treatment for people with arthritis. Another study found that vitamin D deficiency is common in people with rheumatoid arthritis (RA), and may be linked to musculoskeletal pain.
Research has also found that vitamin D may play a significant role in joint health, and that low levels may increase the risk of rheumatologic conditions such as arthritis. Several studies have found low blood levels of vitamin D in patients with osteoarthritis of the hip and knee.
In another study of more than 2,000 people, researchers found that vitamin D deficiency was strongly associated with disabling symptoms among those with rheumatoid arthritis. While it may be true that people with arthritis don't get as much sun exposure — exposure to the sun helps promote vitamin D production in the body — the study authors adjusted for that and still found that being vitamin D deficient was linked to arthritis pain.
ProHydrolase® Maximizes the Performance Benefits Of Our Mobile and Flexible All-In-One Joint Health Formula TM
Physically active people may need additional amino acids due to
the high rate of protein synthesis that occurs when building and
repairing muscle and tissue during and after workouts. This need is also shared by Seniors who – in order to prevent or counteract the serious adverse health consequences of Sarcopenia (loss of muscle mass due to aging) and Dynapenia (loss of muscle strength due to aging) - current scientific nutritional research indicates that they should consume at least half-a-gram of Protein per pound per day after age 65.
The most common amino acid supplementation is obtained as complete protein from whey and egg (while it’s also obtained as incomplete protein from soy or pea, which we definitely do not recommend). These proteins
contain a high concentration of amino acids, however they’re bound together in a peptide complex that must be broken down in order to be utilized. ProHydrolase ® provides the enzymes needed to break down these bound amino acids so they can be fully utilized by the body for muscle building and recovery, as well as for muscle mass gain in Seniors.
the high rate of protein synthesis that occurs when building and
repairing muscle and tissue during and after workouts. This need is also shared by Seniors who – in order to prevent or counteract the serious adverse health consequences of Sarcopenia (loss of muscle mass due to aging) and Dynapenia (loss of muscle strength due to aging) - current scientific nutritional research indicates that they should consume at least half-a-gram of Protein per pound per day after age 65.
The most common amino acid supplementation is obtained as complete protein from whey and egg (while it’s also obtained as incomplete protein from soy or pea, which we definitely do not recommend). These proteins
contain a high concentration of amino acids, however they’re bound together in a peptide complex that must be broken down in order to be utilized. ProHydrolase ® provides the enzymes needed to break down these bound amino acids so they can be fully utilized by the body for muscle building and recovery, as well as for muscle mass gain in Seniors.
ProHydrolase® and the Bioactive Peptides in both Non-Denatured Whey Protein Isolate and FORTIGEL® Hydrolyzed Bovine Collagen
ProHydrolase® is a unique blend of proteases that quickly and effectively degrades proteins to small peptides. These
peptides can be used for both their amino acid content, as well as for their functional bioactive peptides.
Bioactive peptides have been defined as “specific protein fragments that have a positive impact on body functions and conditions”. Specifically, the peptides present in milk (whey) and in hydrolyzed bovine collagen (HBCP) have been shown to have intestinal anti-inflammatory, as well as immune function - protective activities, among many other health benefits.
In the case of Hydrolyzed Bovine Collagen Peptides (HBCP) - like the ones our product’s 10 grams/serving of FORTIGEL® supply us with - we must point out that while all forms of Collagen are beneficial to health, studies show that the absorption rate of HBCP is over 90% compared to only 27% or less Collagen absorbable from our food intake.
HBCP also provides the human body with high amounts of both immune function-protective amino acid Proline and amino acid Glycine(essential to build healthy DNA and RNA strands and form Creatine). What the addition of Prohydrolase® does here is to assist in increasing that high-absorbable % already provided by HBCP and make it even more efficient for promoting health.
ProHydrolase® is a scientifically-proven ingredient designed to help build muscle mass and accelerate muscle recovery when used as a component of our Mobile and Flexible All-In-One Joint Health Formula TM formulation, as it digests protein into bio-usable form, taking full advantage of the availability of essential amino acids, that the body so especially needs to maximize after calisthenic activity.
Regarding our non-denatured Whey Isolate, two separate clinical studies have demonstrated the benefits of adding ProHydrolase® to whey protein isolate, as per its proven ability to increase amino acids in the blood by 20% (compared to consuming whey protein alone), thus helping to more effectively build muscle mass and accelerate muscle recovery. A reduction in C-Reactive Protein level (recognized as a clinical bio-marker of internal body inflammation) was also attained due to the beneficial activity of these bioactive peptides in the study participants.
peptides can be used for both their amino acid content, as well as for their functional bioactive peptides.
Bioactive peptides have been defined as “specific protein fragments that have a positive impact on body functions and conditions”. Specifically, the peptides present in milk (whey) and in hydrolyzed bovine collagen (HBCP) have been shown to have intestinal anti-inflammatory, as well as immune function - protective activities, among many other health benefits.
In the case of Hydrolyzed Bovine Collagen Peptides (HBCP) - like the ones our product’s 10 grams/serving of FORTIGEL® supply us with - we must point out that while all forms of Collagen are beneficial to health, studies show that the absorption rate of HBCP is over 90% compared to only 27% or less Collagen absorbable from our food intake.
HBCP also provides the human body with high amounts of both immune function-protective amino acid Proline and amino acid Glycine(essential to build healthy DNA and RNA strands and form Creatine). What the addition of Prohydrolase® does here is to assist in increasing that high-absorbable % already provided by HBCP and make it even more efficient for promoting health.
ProHydrolase® is a scientifically-proven ingredient designed to help build muscle mass and accelerate muscle recovery when used as a component of our Mobile and Flexible All-In-One Joint Health Formula TM formulation, as it digests protein into bio-usable form, taking full advantage of the availability of essential amino acids, that the body so especially needs to maximize after calisthenic activity.
Regarding our non-denatured Whey Isolate, two separate clinical studies have demonstrated the benefits of adding ProHydrolase® to whey protein isolate, as per its proven ability to increase amino acids in the blood by 20% (compared to consuming whey protein alone), thus helping to more effectively build muscle mass and accelerate muscle recovery. A reduction in C-Reactive Protein level (recognized as a clinical bio-marker of internal body inflammation) was also attained due to the beneficial activity of these bioactive peptides in the study participants.
More Health Benefits Attained With ProHydrolase®
In order to add even more nutritional value to our Mobile and Flexible All-In-One Joint Health Formula TM , we’ve incorporated ProHydrolase® as a key component of our product.
We’ve previously described in detail some of its many benefits but still there are more, as this unique, clinically-researched, proprietary digestive enzyme blend of proteases represents an amazing breakthrough in protein nutrition for those people using protein supplements (like Whey Protein Isolate and Bovine Collagen) on a daily basis to fulfill the body’s demanding needs for this vital macro-nutrient, as is the case of endurance athletes, body builders, or anyone with an active lifestyle, as well as Seniors and other adults facing Osteoarthritis (OA).
For example, if you’re a serious Endurance Athlete - who definitely needs considerable daily amounts of Protein, as your body must effectively meet its high demands for maintenance, repair & growth of muscle mass, as well as achieve an optimal muscle recovery and a balanced, thus healthy immune system function - supplementing with our nutritional supplement is a must , especially if you consider that our product offers a superior intake of two top-notch Proteins in the market, namely Whey Isolate (20 grams per serving) and FORTIGEL® Bovine Collagen Peptides (10 grams per serving)- and the fact that Prohydrolase® maximizes their digestibility and bio-availability in your body.
Let’s see how it accomplishes these important benefits.
For example, if you’re a serious Endurance Athlete - who definitely needs considerable daily amounts of Protein, as your body must effectively meet its high demands for maintenance, repair & growth of muscle mass, as well as achieve an optimal muscle recovery and a balanced, thus healthy immune system function - supplementing with our nutritional supplement is a must , especially if you consider that our product offers a superior intake of two top-notch Proteins in the market, namely Whey Isolate (20 grams per serving) and FORTIGEL® Bovine Collagen Peptides (10 grams per serving)- and the fact that Prohydrolase® maximizes their digestibility and bio-availability in your body.
Let’s see how it accomplishes these important benefits.
*ProHydrolase® can increase protein absorption by up to 3 times , as it helps pre-digest protein into bio-usable form, so that amino acid levels in the bloodstream are up to 55 times higher compared to other leading protein enzymes on the market today.
*It supports muscle mass building and improves (accelerates) recovery time, thus maximizing the performance benefits of protein supplementation – as it assists the body in absorbing more of the macro-nutrient rather than excreting it.
* It helps ensure smaller, non-immunogenic protein peptides are formed which helps lower inflammation in the body as scientifically indicated by decreased CRP levels.
* It helps reduce discomfort such as gas, diarrhea and bloating which are often associated with protein consumption due to peptide sensitivity, which could happen when protein is not broken down into its smallest composition.
*It supports muscle mass building and improves (accelerates) recovery time, thus maximizing the performance benefits of protein supplementation – as it assists the body in absorbing more of the macro-nutrient rather than excreting it.
* It helps ensure smaller, non-immunogenic protein peptides are formed which helps lower inflammation in the body as scientifically indicated by decreased CRP levels.
* It helps reduce discomfort such as gas, diarrhea and bloating which are often associated with protein consumption due to peptide sensitivity, which could happen when protein is not broken down into its smallest composition.
ProHydrolase® is a registered trademark of Deerland Enzymes, Inc.
Its Unique Combination of Excellent Sweeteners Also Enhance The Nutritional Quality of Our Mobile and Flexible All-In-One Joint Health Formula TM
Our nutritional supplement is sweetened with plant-based, non-caloric Stevia, in combination with Palatinose® (Isomaltulose)- which is a naturally sourced ‘smart’ sugar, as it is the market’s only fully but slowly digestible-low glycemic carbohydrate.
Research has shown that Stevia sweeteners do not contribute calories or carbohydrates to the diet, and very importantly to health – that they do not affect blood glucose or insulin response.
On the other hand, Palatinose® (Isomaltulose) provides balanced and longer lasting energy - plus enhanced post-exercise rehydration - for optimized physical and mental performance in the form of glucose (the only energy our brain can use directly and a direct source of energy for our muscles), thus also (as Stevia does) helping prevent unhealthy high spikes in both blood glucose and blood insulin levels.
It is derived from sugar beet, and provides full carbohydrate energy (4kcal per gram) – which is essential for physical exercise performance – over a longer period of time and in a balanced way, plus the fact that unlike non-natural sweeteners, it is actually a carbohydrate, meaning that it does eventually break down into sugars in the body and provides an actual nutritional benefit. *Research at the German Institute of Human Nutrition in Potsdam-Rehbrucke, demonstrated that Palatinose® has a favorable metabolic effect on the blood glucose management for people with Diabetes mellitus type 2 (*Study published on the March 2016 issue of Diabetes Care).
In addition, Palatinose® (Isomaltulose) helps improve fat oxidation during physical activity, leading to prolonged energy supply. Being acid stable, it can support better rehydration after exercise – a very important advantage for sports and exercise performance. And last but not least, Palatinose® (Isomaltulose) is the first non-cariogenic (“tooth-friendly”) sugar, thus is now utilized in the confection of chewing gums.
Note : Many of the artificial (non-natural) sweeteners approved for consumer use - such as aspartame, sucralose. saccharin, neotame, and acesulfame potassium, etc. – may introduce health and nutrition concerns that meet or exceed those of natural sugar sources. That’s why we also avoided them when selecting sweetening ingredients for our formulation.
Research has shown that Stevia sweeteners do not contribute calories or carbohydrates to the diet, and very importantly to health – that they do not affect blood glucose or insulin response.
On the other hand, Palatinose® (Isomaltulose) provides balanced and longer lasting energy - plus enhanced post-exercise rehydration - for optimized physical and mental performance in the form of glucose (the only energy our brain can use directly and a direct source of energy for our muscles), thus also (as Stevia does) helping prevent unhealthy high spikes in both blood glucose and blood insulin levels.
It is derived from sugar beet, and provides full carbohydrate energy (4kcal per gram) – which is essential for physical exercise performance – over a longer period of time and in a balanced way, plus the fact that unlike non-natural sweeteners, it is actually a carbohydrate, meaning that it does eventually break down into sugars in the body and provides an actual nutritional benefit. *Research at the German Institute of Human Nutrition in Potsdam-Rehbrucke, demonstrated that Palatinose® has a favorable metabolic effect on the blood glucose management for people with Diabetes mellitus type 2 (*Study published on the March 2016 issue of Diabetes Care).
In addition, Palatinose® (Isomaltulose) helps improve fat oxidation during physical activity, leading to prolonged energy supply. Being acid stable, it can support better rehydration after exercise – a very important advantage for sports and exercise performance. And last but not least, Palatinose® (Isomaltulose) is the first non-cariogenic (“tooth-friendly”) sugar, thus is now utilized in the confection of chewing gums.
Note : Many of the artificial (non-natural) sweeteners approved for consumer use - such as aspartame, sucralose. saccharin, neotame, and acesulfame potassium, etc. – may introduce health and nutrition concerns that meet or exceed those of natural sugar sources. That’s why we also avoided them when selecting sweetening ingredients for our formulation.
- Nelson Gonzalez, MD and Augusto Agostini, PhD / DOCTORS’ Wellness Factors LLC